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September 10, 2025JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCHOpen Access

Pathological Response Assessment following Long Course Neoadjuvant Chemoradiation in Locally Advanced Rectal Cancer: A Single Institutional Cohort Study

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Authors

MBM BabyJRJ. RaphaelBRB Rajkrishna

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Overview

Observational analysis reported an 86% two-year disease-free survival in patients with locally advanced rectal cancer, indicating effective neoadjuvant chemoradiation.

Key Points

  • Pathological tumour regression was observed in patients undergoing neoadjuvant chemoradiation, enhancing treatment outcomes.
  • The two-year disease-free survival rate was reported at 86%, suggesting potential long-term benefits of the treatment.
  • Most participants presented with T3 disease, with Mandard TRG results varying among patients after treatment.
  • The findings support the role of neoadjuvant chemoradiation in improving pathological response in locally advanced rectal cancer.

Cite This Study

Baby et al. (2025) studied this question.

synapsesocial.com/papers/68c1aac654b1d3bfb60e332ahttps://doi.org/10.7860/jcdr/2025/78942.21355
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