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September 10, 2025Parasite Epidemiology and ControlOpen Access

Rare detection of dermal Leishmania infantum in two pediatric patients with cutaneous leishmaniasis (CL) in southern Iran

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Authors

MKMohsen KalantariKAKourosh AziziQAQasem Asgari

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Overview

Observational analysis reveals dermal leishmania in pediatric patients with cutaneous leishmaniasis, highlighting atypical manifestations.

Key Points

  • Detection of Leishmania infantum underscores atypical dermal manifestations in pediatric patients.
  • Molecular assays confirmed presence of L. infantum through PCR targeting the cpb gene, with 702/741-bp amplicons.
  • Phylogenetic analysis details cases linked to a strain closely related to the LIPA59 genotype, challenging traditional associations.
  • Enhanced surveillance integrating PCR methods is critical to address the dual burden of cutaneous and visceral leishmaniasis.

Cite This Study

Kalantari et al. (2025) studied this question.

synapsesocial.com/papers/68c1aac654b1d3bfb60e33fchttps://doi.org/10.1016/j.parepi.2025.e00452
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Molecular Identification of <i>Leishmania</i> Species in Kurdistan Province, Western Iran2025
  2. 2First report of Leishmania RNA virus 2 and its high genetic diversity in cutaneous leishmaniasis cases from Ilam Province, Iran2025
  3. 3Molecular Investigation of Cutaneous Leishmaniasis (CL) from Biopsy Samples: A Case Study of District Mohmand, KPK2024
  4. 4Detection and phylogenetic analysis of kinetoplast DNA of Leishmania infantum infected humans, domestic dogs and sandflies in Northwest Iran2024 · 1 citations
  5. 5Diagnostic challenges in cutaneous leishmaniasis due to atypical Leishmania infantum: pathologists’ insights from re-emergence zones2024 · 5 citations