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September 10, 2025BMC Medical GenomicsOpen Access

First report of Leishmania RNA virus 2 and its high genetic diversity in cutaneous leishmaniasis cases from Ilam Province, Iran

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Authors

RSReza SaberiALAndreia Barcelos de Passos LimaHHHoma Hajjaran

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Overview

This research identifies LRV2 in cutaneous leishmaniasis patients and reveals significant genetic diversity, highlighting potential implications for disease transmission.

Key Points

  • LRV2 was identified in 12.5% of 32 cutaneous leishmaniasis patients, indicating its presence in western Iran.
  • Phylogenetic analysis revealed high genetic diversity among LRV2 isolates with 96-99% sequence identity to strains from neighboring countries.
  • The study utilized PCR analysis to detect LRV2, contributing important data for understanding its role in cutaneous leishmaniasis.
  • Findings suggest high genetic variability in LRV2 may impact its pathogenesis and transmission dynamics in affected regions.

Cite This Study

Saberi et al. (2025) studied this question.

synapsesocial.com/papers/68c1ce6754b1d3bfb60f56f3https://doi.org/10.1186/s12920-025-02198-1
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The prevalence of Leishmania RNA virus in cutaneous leishmaniasis: a meta-analysis and systematic review2025 · 4 citations
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