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September 10, 2025Pediatric DiabetesOpen Access

Celiac Disease in Children With Type 1 Diabetes: The Usefulness of Screening— 25 years of Experience in a Single Center

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Authors

RSRoland SchweizerJBJulia BungDMDavid Majer

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Overview

Retrospective analysis highlights the screening value for celiac disease in children with type 1 diabetes, indicating it should focus on symptomatic cases.

Key Points

  • Children with type 1 diabetes are significantly at risk for celiac disease, with about 122 showing positive CD-specific antibodies.
  • Despite a high incidence of elevated antibodies, only 12 were diagnosed with celiac disease, showing the importance of symptoms in diagnosis.
  • Screening for celiac disease through antibody tests is most effective in children exhibiting symptoms such as poor growth and gastrointestinal issues.
  • Long-term antibody positivity varied, with some children showing improvements even without strict gluten-free diets throughout the observation period.

Cite This Study

Schweizer et al. (2025) studied this question.

synapsesocial.com/papers/68c1aacc54b1d3bfb60e37b0https://doi.org/10.1155/pedi/4717290
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Challenge of diagnosing celiac disease in pediatric type 1 diabetes mellitus: lessons from long-term serological surveillance2026
  2. 2Celiac Disease Among Patients with Type 1 Diabetes Mellitus2025
  3. 323 Time trend and potential risk factors for celiac disease development in children with type 1 diabetes mellitus: 10-year single center experience in the emirate of Abu Dhabi- UAE2024 · 1 citations
  4. 4Prevalence and predictive factors for celiac disease in children with type 1 diabetes. Whom and when to screen?A nationwide longitudinal cohort study of Swedish children2024
  5. 5Prevalence and predictive factors for celiac disease in children with type 1 diabetes. Whom and when to screen?A nationwide longitudinal cohort study of Swedish children2024