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September 10, 2025Innovative Journal of PediatricsOpen Access

Tenofovir Disoproxil Fumarate Prevents Mother-to-Child Transmission of Hepatitis B Virus: A Comprehensive Assessment from the Systematic Review and Meta-Analysis

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Authors

LYLi YCYChao YangZCZhiwei Chen

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Overview

Systematic review reveals tenofovir disoproxil fumarate significantly reduces mother-to-child transmission of HBV, indicating effective prevention strategies.

Key Points

  • Tenofovir disoproxil fumarate significantly reduces mother-to-child transmission of hepatitis B virus.
  • The pooled odds ratio suggests a notable reduction in transmission with an OR of 0.38, highlighting TDF's effectiveness.
  • This systematic review and meta-analysis included 43 randomized controlled trials assessing TDF's impact on HBV transmission.
  • The findings support incorporating tenofovir disoproxil fumarate into maternal health programs, emphasizing improved prevention strategies.

Cite This Study

Y et al. (2025) studied this question.

synapsesocial.com/papers/68c1abf154b1d3bfb60e3c73https://doi.org/10.5812/ijpediatr-157773
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