This review discusses design strategies for nanocarriers improving drug delivery in cancer and infectious diseases, indicating better therapeutic outcomes.
Effective drug delivery requires overcoming multiple biological barriers, including enzymatic degradation, immune clearance, and poor tissue penetration. This review systematically presents the design strategies for nanocarriers — including surface modification, stimuli-responsive release, and active targeting ligands — to enhance therapeutic index and specificity. We discuss recent advances in polymeric nanoparticles, liposomes, dendrimers, and exosome-based carriers, emphasizing their applications in cancer, infectious diseases, and neurological disorders
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Temimi et al. (2025) studied this question.
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