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September 10, 2025Acta OphthalmologicaOpen Access

SD‐OCT‐based biomarkers in predicting treatment outcomes of macular oedema secondary to retinal vein occlusion treated with anti‐VEGF therapy

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Authors

KTKen K. TsangChinese University of Hong KongVHVivian W.K. HuiChinese University of Hong KongCPChi Pui PangChinese University of Hong Kong

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Overview

Retrospective cohort study reveals that SD-OCT biomarkers correlate with visual acuity in macular oedema, suggesting utility in therapy response.

Key Points

  • Baseline disrupted EZ/ELM correlated with worse visual acuity over 24 months in macular oedema.
  • Presence of hyper-reflective foci indicated worse baseline visual acuity in the BRVO subgroup.
  • Improvement in DRIL extent and EZ/ELM integrity predicted a 5-letter gain at 12 and 24 months.
  • A comprehensive system of SD-OCT features could enhance prediction of treatment outcomes for macular oedema.

Cite This Study

Tsang et al. (2025) studied this question.

synapsesocial.com/papers/68c1ae7054b1d3bfb60e64c5https://doi.org/10.1111/aos.17574
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