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September 10, 2025

Transdermal Drug Delivery: Advances In Permeation Enhancers and Microneedles

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Authors

RAR S AkshathaThe White HouseMAMs. Harshitha Kumari B AThe White HouseMVMs. Ashwini K VThe White House

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Implication

This review highlights enhancements in drug permeation using microneedles and chemical permeation enhancers, showing their potential in clinical applications.

Key Points

  • Transdermal drug delivery improves patient compliance and reduces first-pass metabolism.
  • Chemical permeation enhancers include alcohols and fatty acids that increase drug permeation effectiveness.
  • Microneedles create microchannels in the skin, allowing better drug delivery with minimal discomfort.
  • The combination of CPEs and microneedles enhances drug flux and delivery potential across a range of molecules.

Cite This Study

Akshatha et al. (2025) studied this question.

synapsesocial.com/papers/68c1afc654b1d3bfb60e77bdhttps://doi.org/10.64063/3049-1681.vol.2.issue7.9
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Integration of Nanocarriers and Microneedles for Enhanced Transdermal Drug Delivery: Current Advances and Future Perspectives2026
  2. 2Transdermal Drug Delivery Systems: Methods for Enhancing Skin Permeability and Their Evaluation2025 · 61 citations
  3. 3Advanced Transdermal Delivery Systems: Techniques to Maximize Skin Penetration and Drug Efficacy2026
  4. 4Microneedles: An Efficient Technique to Increase Transdermal Drug Delivery System2024 · 11 citations
  5. 5MICRONEEDLE-BASED DRUG DELIVERY SYSTEMS2026