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September 10, 2025Frontiers in NeurologyOpen Access

Contemporary insights into neuroimmune interactions across development and aging

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Authors

XYXin Yi YeoNational University of SingaporeYCYunseon ChoiPohang University of Science and TechnologyYHYong Shin HongCHA Bundang Medical Center

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Implication

This review explores neuroimmune interactions affecting aging and immunosenescence, highlighting system communications.

Key Points

  • Aging contributes to declines in both neurological and immune system functions, with chronic systemic inflammation being a crucial factor.
  • The review discusses interactions between the nervous and immune systems across different life stages, indicating that these may influence health outcomes.
  • Evidence shows bidirectional communication between the nervous system and the immune system, which can be modulated by the tissue environment.
  • Understanding these interactions may provide insights into age-related neurological decline and immune system aging.

Cite This Study

Yeo et al. (2025) studied this question.

synapsesocial.com/papers/68c1afcd54b1d3bfb60e7b39https://doi.org/10.3389/fneur.2025.1611124
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