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September 10, 2025JAMA Network OpenOpen Access

Adolescent Body Mass Index, Weight Trajectories to Adulthood, and Osteoporosis Risk

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There was a significant inverse relationship between adolescent BMI and osteoporosis risk in adulthood.
The incidence rate of osteoporosis varied significantly with weight categories, falling from 330.2 to 78.9 per 100,000 person-years.
Cox proportional hazard models analyzed the associations between BMI trajectories and osteoporosis from a cohort study.
Findings emphasize the importance of weight stability from adolescence to adulthood, particularly in underweight individuals.

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Cohort study shows adolescent body mass index associations with osteoporosis risk in adulthood, highlighting weight changes as critical.

Simchoni et al. (2025) studied this question.

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