Why the study?
Does elevated adolescent BMI increase the risk of incident diabetes and coronary heart disease in young men?
Population
37,674 apparently healthy young men, first measured at 17 years of age, from the Israeli Army Medical Corps.
Comparison
Elevated adolescent BMI (highest decile) vs Lowest decile of adolescent BMI
Design
Cohort
Follow-up
mean 17.4 years
Authors
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Adolescent BMI independently associated with midlife CHD; leaves open causal mechanisms and whether early intervention alters risk beyond adult BMI.
Does elevated adolescent BMI increase the risk of incident diabetes and coronary heart disease in young men?
Elevated adolescent BMI independently increases the risk of coronary heart disease in midlife regardless of adulthood BMI, whereas its effect on diabetes risk is mediated by adulthood BMI.
Tirosh et al. (2011) studied this question.
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