This protocol outlines the extraction of pcb18 and its metabolites from serum, indicating effective analysis methods.
This protocol describes the extraction of 2,2′,5-trichlorobiphenyl (PCB18) and its monohydroxylated metabolites from mouse blood or serum using liquid-liquid extraction followed by solid-phase extraction cleanup. The levels of PCB18 and OH-PCB11s in the blood/serum samples are subsequently measured by gas chromatography-tandem mass spectrometry.
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Li et al. (2025) studied this question.
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