After PCI with DES followed by DAPT, clopidogrel reduced MACCE vs. aspirin monotherapy at 2 y in patients with high risk for recurrence

Ellis Lader

doi:10.7326/annals-25-02854-jc

August 4, 2025Annals of Internal Medicine

After PCI with DES followed by DAPT, clopidogrel reduced MACCE vs. aspirin monotherapy at 2 y in patients with high risk for recurrence

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Key Points

Clopidogrel usage resulted in a lower rate of MACCE at 2 years compared to aspirin monotherapy.
The MACCE rate was significantly reduced among patients on clopidogrel vs. aspirin at the two-year mark.
Analysis after PCI involved patients treated with DES and DAPT, emphasizing the role of clopidogrel.
Findings support the use of clopidogrel in high-risk populations to prevent recurrence of adverse events.

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Implication

Observational analysis reduced MACCE in patients receiving clopidogrel vs. aspirin monotherapy, indicating clopidogrel's potential for high-risk patients.

Abstract

GIM/FP/GP: [Formula: see text] Cardiology: [Formula: see text].

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Ellis Lader (2025) studied this question.

synapsesocial.com/papers/68c1b18b54b1d3bfb60e87f4 https://doi.org/10.7326/annals-25-02854-jc

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After PCI with DES followed by DAPT, clopidogrel reduced MACCE vs. aspirin monotherapy at 2 y in patients with high risk for recurrence

Key Points

No abstract yet

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

After PCI with DES followed by DAPT, clopidogrel reduced MACCE vs. aspirin monotherapy at 2 y in patients with high risk for recurrence

Key Points

No abstract yet

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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