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September 10, 2025

F-FDG parameters as therapy response predictors in patients with diffuse large B-cell lymphoma: A single centre experience.

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Authors

MKMilica KoturUniversity of BelgradeNPNikola PantićUniversity of BelgradeIMIsidora Grozdić MilojevićUniversity of Belgrade

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Implication

Observational analysis found Deauville score predicts outcomes in diffuse large B-cell lymphoma, highlighting the role of metabolic response.

Key Points

  • Early metabolic response assessed via interim 18F-FDG PET/CT is a significant predictor of disease outcome in diffuse large B-cell lymphoma.
  • Patients with an international prognostic index score of 2 or less and Deauville score of 3 or less experienced longer progression-free survival.
  • Among the clinical-demographic parameters analyzed, the international prognostic index score was the sole significant predictive factor.
  • The study involved 64 patients who underwent 18F-FDG PET/CT imaging before and after chemotherapy treatment.

Cite This Study

Kotur et al. (2025) studied this question.

synapsesocial.com/papers/68c1b34d54b1d3bfb60e9c44https://doi.org/10.1967/s002449912802
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Evaluation of therapeutic effect and prognostic value of 18F-FDG PET/CT in different treatment nodes of DLBCL patients2024 · 9 citations
  2. 2Application effect of 18F-FDG PET/CT technique in diagnosis and prognosis evaluation of lymphoma2024 · 3 citations
  3. 3Assessment of the efficacy and prognostic value of 18F-FDG PET-CT using deauville 5-point scale and ΔSUVmax methods in diffuse large B-cell lymphoma patients2025 · 2 citations
  4. 4FDG‐PET/CT after two cycles of R‐CHOP in DLBCL predicts complete remission but has limited value in identifying patients with poor outcome – final result of a UK National Cancer Research Institute prospective study2020 · 42 citations
  5. 5Prognostic Value of Semi-Quantitative Metabolic Parameters on [18F]FDG PET/CT in Patients with Diffuse Large B-Cell Lymphoma at Diagnosis2026