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In vivo analysis showed that helicteres isora root extract lowers blood glucose levels in diabetic rats, suggesting a potential therapeutic option.
Helicteres Isora root is a well-known antidiabetic medicinal plant used for several traditional medicine aspects in different areas of the world, including India. This study includes phytochemical analysis, antidiabetic evaluation. The root of Helicteres Isora has been used in traditional health systems to treat diabetes mellitus in India. However, the antidiabetic activity of this medicinal plant is not scientifically validated and authenticated. The present study aimed to investigate the in vitro and in vivo anti-diabetic activity of root crude extract and solvent fractions of Helicteres Isora. The aim of this study was to investigate the antidiabetic activity and mechanism of action of Ethanolic extract prepared from Helicteres Isora root. Since this claim has not been investigated scientifically, the aim of this study was to evaluate the antidiabetic effect and phytochemical screening of Streptozotocin -induced diabetic Rats. The result demonstrated the beneficial biochemical effects of Helicteres Isora root extract by inhibiting α–amylase improving serum lipid profile levels. The root crude extract are effective in lowering blood glucose levels in diabetic and hypoglycemic rats. The claimed traditional use as antidiabetic has scientific ground.
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Madhushalini et al. (2025) studied this question.
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