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September 10, 2025International Journal of Science and Technology Research Archive

Topical aloe vera and hyaluronic acid accelerate healing of skin graft donor sites in Wistar rats

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Authors

IAI Wayan Gede Bandem ARIMBAWAAHAgus Roy Rusly Hariantana HamidINI Wayan Niryana

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Overview

Randomized control trial shows faster epithelialization and increased collagen in STSG donor sites with Aloe vera and HA treatment.

Key Points

  • Significantly higher fibroblast counts were observed in the Aloe vera-HA treatment group on day 7.
  • Collagen density increased notably with the Aloe vera-HA treatment compared to paraffin gauze on day 7.
  • Epithelialization was significantly faster in the Aloe vera-HA group at days 7 and 14.
  • The study emphasizes the potential of Aloe vera and hyaluronic acid as effective alternatives to paraffin gauze for skin graft care.

Cite This Study

ARIMBAWA et al. (2025) studied this question.

synapsesocial.com/papers/68c1b36054b1d3bfb60ea574https://doi.org/10.53771/ijstra.2025.9.1.0045
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1COMPARATIVE STUDY BETWEEN THE EFFECTIVENESS OF AMNION-CollaGee [COLLAGEN–GELATIN–ELASTIN] AS A BIOLOGICAL PRODUCT WOUND DRESSING AND CONVENTIONAL DRESSING ON THE DONOR SITE OF THE SPLIT THICKNESS SKIN GRAFT IN ANIMALS MODEL (RATS)2024
  2. 2Morphological analysis of wound healing with the use of aloe extract, hydrogel and their combination (experimental research)2024
  3. 3Effect of Dextran‐Aminated Hyaluronic Acid Hydrogel on the Repair of Different Degrees of Epidermal Injury2025
  4. 4Comparative effects of aloe vera and its combination with silver sulfadiazine on incision wound healing in Wistar rats2025
  5. 5Effect of Aqueous Extract Iraqi Aloe vera on Treatment of Skin Wounds in Rabbits2025