Laboratory study demonstrates higher efficacy against staphylococcus aureus than e coli, suggesting practical disinfectant use.
The disinfecting properties of a new composite bactericide of domestic production have been studied in laboratory conditions. A higher sensitivity of St. aureus strain 209-P (2nd group of resistance to chemical disinfectants) to the disinfectant was established than that of E. coli strain 1257 (1st group of resistance). Thus, the bactericidal dilution of the test agent against Staphylococcus aureus without protein was 1:41834.1 at an exposure of 10 minutes and 1:58567.8 at an exposure of 30 minutes; in the presence of protein - 1:7778.4 and 1:10889.8 at an exposure of 10 and 30 minutes, respectively. The protein index (PI) of the product was 5.38. The bactericidal dilution of the test agent against E. coli in the absence of protein was 1:10889.9 at an exposure of 10 minutes and 1:15245.7 at an exposure of 30 minutes, and in the presence of protein (inactivated horse blood serum) – 1:1446.3 and 1:2024.8 at an exposure of 10 and 30 minutes, respectively. The PI of the disinfectant is 7.53. Disinfection of smooth test surfaces, artificially contaminated St. aureus strain 209-P were disinfected with 0.1% solution, rough – 0.5% concentration, at an exposure of 3 hours and the consumption rate of 0.25-0.5 l/m2 for all types of surfaces. Disinfection of artificially infected E. coli strain 1257 test surfaces was achieved: 0.1% (smooth), rough – 0.7% concentration of the agent at an exposure of 1 hour and at a consumption rate of 0.25 – 0.5 l/m2 for both types of surfaces.
No takes yet. Share an insight, caveat, or question.
Kuvshinchikov et al. (2025) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: