Analysis of histological techniques and imaging tools for retinal pigment epithelium evaluation, highlighting modern diagnostic approaches.
The paper analyzes modern literature on the main morphological methods to study retinal pigment epithelium in cell cultures. To diagnose retinal pigment epithelium pathologies, the following approaches are used: histological and histochemical methods, optical coherence tomography, RPS-Net, RT-PCR test, and morphological evaluation of retinal pigment epithelium with autofluorescence. These tools allow us to determine the main structural and cytogenetic features of the retinal pigment epithelium based on its qualitative and quantitative characteristics. Modern diagnostic techniques focus on early detection of retinal pathology and the development of effective diagnostic protocols, including advancements in existing techniques. In particular, minimally invasive diagnostic tools for assessing retinal pigment epithelium pathology warrant further targeted research.
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Борзенок et al. (2025) studied this question.
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