Case report reveals a novel interventional approach for mechanical aortic valve thrombosis, indicating potential for high-risk patients.
Mechanical heart valves offer long-term durability but carry a risk of thrombosis, even with therapeutic anticoagulation. We present a case of a patient with a history of Bentall procedure and bovine aortic arch who developed a thrombotic stuck mechanical aortic valve. Despite therapeutic international normalized ratio and administration of thrombolytics, the obstruction persisted. Given the patient's high surgical risk, a novel percutaneous interventional approach was used, resulting in restoration of valve function and a favorable clinical outcome. Mechanical valve thrombosis is a rare but life-threatening condition with an incidence of 0.1% to 5.7%. Although subtherapeutic international normalized ratio is a common cause, cases may occur despite adequate anticoagulation. This report highlights an innovative, catheter-based management strategy in a complex anatomical setting, emphasizing the need for alternative therapies in nonsurgical candidates. Mechanical valve thrombosis can occur even with optimal anticoagulation. Novel interventional solutions may be lifesaving in select high-risk patients.
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Almusawi et al. (2025) studied this question.
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