Red-Light-Triggered Microenvironment-Responsive Sustained Carbon Monoxide Release for Enhanced Tumor Therapy

Jiahui Sheng; Yao Wang; Fei Li; Guihai Gan; Yao Lu; Le‐Wei Li; Jian Cheng

doi:10.1039/d5tb01166c

January 1, 2025Journal of Materials Chemistry B

Red-Light-Triggered Microenvironment-Responsive Sustained Carbon Monoxide Release for Enhanced Tumor Therapy

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Key Points

Microenvironment-responsive carbon monoxide release significantly enhances tumor therapy.
The delivery system utilizes a Pd photosensitizer to achieve controlled and sustained CO release.
Light-gated mechanisms allow for precise activation in cancer treatment settings.
These findings may lead to new strategies for improving the effectiveness of cancer therapies.

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Implication

This innovative approach enables controlled CO release in tumors, highlighting its potential for enhanced cancer therapy.

Abstract

Light-gated, microenvironment-responsive CO and Fe²⁺ delivery system based on diiron hexacarbonyl in a micelle with amines and a Pd photosensitizer enables controlled, sustained release for cancer therapy.

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Cite This Study

Sheng et al. (2025) studied this question.

synapsesocial.com/papers/68c1b82654b1d3bfb60ec8d8 https://doi.org/10.1039/d5tb01166c

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Red-Light-Triggered Microenvironment-Responsive Sustained Carbon Monoxide Release for Enhanced Tumor Therapy

Key Points

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Implication

Abstract

Discussion

Cite This Study

Red-Light-Triggered Microenvironment-Responsive Sustained Carbon Monoxide Release for Enhanced Tumor Therapy

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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