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September 10, 2025International Journal of Molecular SciencesOpen Access

Investigating the Potential of Propranolol as an Anti-Tumor Agent in Colorectal Cancer Cell Lines

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Authors

SAShiekhah Mohammad AlzahraniHDHuda A. Al DoghaitherHAHind Ali Alkhatabi

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Overview

Investigating propranolol's anti-tumor activity in colorectal cancer cell lines, highlighting its potential synergy with chemotherapy.

Key Points

  • Propranolol suppressed cell proliferation and induced apoptosis in colorectal cancer cell lines, highlighting its anti-tumor potential.
  • The combination of propranolol and capecitabine showed a synergistic effect, enhancing therapeutic outcomes in colorectal cancer.
  • HT-29 cells exhibited the highest sensitivity to propranolol regarding cytotoxicity and ROS generation during treatment.
  • Variations in how different colorectal cancer cell lines respond to propranolol suggest the importance of genetic diversity in treatment approaches.

Cite This Study

Alzahrani et al. (2025) studied this question.

synapsesocial.com/papers/68c1bb5b54b1d3bfb60ecd20https://doi.org/10.3390/ijms26157513
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