What type of study is this?

This is a In Silico Study study.

Discovery of potent inhibitors of NS4B protein of dengue virus type 2 from natural compounds: An in silico approach

View Full Paper

Ask AI

Bookmark

Authors

This in silico approach identifies potential natural inhibitors of NS4B protein in DENV2, suggesting effective therapeutic options.

D155 and D170 acted as potent inhibitors of NS4B protein, presenting a promising route for dengue treatment.
Binding affinity for both compounds measured below -20 kcal/mol, indicating strong potential interactions with DENV2 NS4B.
Molecular docking simulations showed stable interactions of these compounds with the NS4B protein over 200 ns.
Natural compounds from Valeriana hardwickii and Glinus oppositifolius provide a new avenue for dengue drug discovery.

Pham et al. (2025) studied this question.

View Full Paper

Ask AI

Bookmark

View Full Paper

Ask AI

Bookmark

Authors

This in silico approach identifies potential natural inhibitors of NS4B protein in DENV2, suggesting effective therapeutic options.

D155 and D170 acted as potent inhibitors of NS4B protein, presenting a promising route for dengue treatment.
Binding affinity for both compounds measured below -20 kcal/mol, indicating strong potential interactions with DENV2 NS4B.
Molecular docking simulations showed stable interactions of these compounds with the NS4B protein over 200 ns.
Natural compounds from Valeriana hardwickii and Glinus oppositifolius provide a new avenue for dengue drug discovery.

Pham et al. (2025) studied this question.

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

View Full Paper

Ask AI

Bookmark