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September 10, 2025Y HOC TP HO CHI MINH

Carbapenem resistence and Carbapenemase classification of Enterobacteriaceae in Intensive Care Unit: A cross-sectional study

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Authors

HLHương Giang LêLDLuan Minh DangNPNgan Truong Thi Pham

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Overview

Cross-sectional study assessed carbapenem-resistant Enterobacteriaceae prevalence and carbapenemase genes in ICU patients, highlighting antibiotic resistance challenges.

Key Points

  • Of 89 Enterobacteriaceae isolates, 51 were carbapenem-resistant, indicating a high prevalence in ICU patients.
  • Among carbapenem-resistant isolates, K. pneumoniae was the most common (70.8%), followed by S. marcescens (92.3%).
  • Class D carbapenemase was the most prevalent, found in 76.5% of resistant isolates, linking multiple gene carriage to higher antibiotic resistance.
  • Increased infection control measures are essential due to the significant risk of spreading multidrug-resistant pathogens.

Cite This Study

Lê et al. (2025) studied this question.

synapsesocial.com/papers/68c1bb5b54b1d3bfb60ecf81https://doi.org/10.32895/mpr.25.00001
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Also Consider

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  2. 2Phenotypic and Genotypic Detection of Carbapenem Resistance in Urinary Enterobacterales Isolates: A Prospective Cross-Sectional Diagnostic Evaluation Study2026
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  4. 4Carbapenemases Produced by Multidrug-Resistant Strains of <i>Klebsiella Pneumoniae</i> Isolated from Intensive Care Patients2024 · 2 citations
  5. 5Carbapenemase-encoding genes in critical gram-negative bacteria isolated from ICU patients with infections and/or gastrointestinal carriage, and environmental samples in the amhara National Regional state, Ethiopia2025