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September 10, 2025Scientific ReportsOpen Access

Reproductive toxicity in male rats induced by chronic arsenic exposure involves hormonal and structural changes

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Authors

SMSoltanali MahboobTabriz University of Medical Sciences SJSarwat JahanQuaid-i-Azam University HBHussain BadshahQuaid-i-Azam University

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Implication

Observational analysis reveals decreased sperm motility and hormonal imbalance in male rats after arsenic exposure, indicating significant reproductive toxicity.

Key Points

Chronic arsenic exposure significantly reduces sperm motility and viability in male rats.
High-dose arsenic treatment shows marked alterations in hormonal levels, including testosterone and FSH.
Histopathological analysis reveals severe damage to seminiferous tubules and testosterone-producing Leydig cells.
Arsenic-induced oxidative stress correlates with increased DNA fragmentation in sperm, suggesting potential impact on fertility.

Cite This Study

Mahboob et al. (2025) studied this question.

synapsesocial.com/papers/68c1bd3b54b1d3bfb60ee713 https://doi.org/10.1038/s41598-025-14929-6

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Implication

Observational analysis reveals decreased sperm motility and hormonal imbalance in male rats after arsenic exposure, indicating significant reproductive toxicity.

Reproductive toxicity in male rats induced by chronic arsenic exposure involves hormonal and structural changes

Discussion

Member takes

Implication

Key Points

Cite This Study

Reproductive toxicity in male rats induced by chronic arsenic exposure involves hormonal and structural changes

Discussion

Member takes

Implication

Key Points

Cite This Study

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