⌘+K

Pulse Explore Clubs Researchers Journals

Home Clubs Explore

July 18, 2025Neurosurgery

Delayed Cerebral Ischemia and Vasospasm After Aneurysmal Subarachnoid Hemorrhage: Impact of Stents and Dual Antiplatelet Therapy

Li L Rachel Jacobs Prateek Agarwal Alhamza R Al‐Bayati Raul G. Nogueira Michael Lang Bradley A. Gross

View Full Paper

Ask AI

Bookmark

Share

Key Points

Patients undergoing dual antiplatelet therapy showed a significant reduction in severe vasospasm, with 37% vs 55% in the control group.
Delayed cerebral ischemia occurred in 24.2% of patients overall, with a numerically lower risk in the S-DAPT group (18% vs 27%), though not statistically significant.
A total of 285 patients with aneurysmal subarachnoid hemorrhage were evaluated, with 29% receiving stent-assisted dual antiplatelet therapy.
Subgroup analysis indicated S-DAPT significantly lowered angiographic vasospasm risks in grade 1-3 aSAH, with a 2-fold reduced risk in multivariate analyses.

No abstract yet

We only have this paper's title and publication details.

Read it at the source→

Implication

Observational analysis shows reduced severity of vasospasm in patients using dual antiplatelet therapy, suggesting a potential benefit for treatment.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

L et al. (2025) studied this question.

synapsesocial.com/papers/68c1bd4254b1d3bfb60eea04 https://doi.org/10.1227/neu.0000000000003621

View Full Paper

Ask AI

Bookmark

Share

Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Dual antiplatelet treatment associated with reduced risk of symptomatic vasospasm and delayed cerebral ischemia in aneurysmal subarachnoid hemorrhagecohort · 2020 · 15 citations
2Safety of dual antiplatelet therapy in the acute phase of aneurysmal subarachnoid hemorrhage: a propensity score–matched studycohort · 2023 · 21 citations
3Effect of Dual Antiplatelet Therapy on Shunt Outcomes in Patients with Aneurysmal Subarachnoid Hemorrhage: A Matched Cohort Pilot Studycohort · 2018 · 5 citations
4External Ventricular Drain and Hemorrhage in Aneurysmal Subarachnoid Hemorrhage Patients on Dual Antiplatelet Therapy: A Retrospective Cohort Studycohort · 2018 · 54 citations
5Analysis of safety, efficacy, and risk factors for poor clinical prognosis of dual antiplatelet therapy after stent-assisted coil embolization for intracranial ruptured aneurysms2025 · 1 citations