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September 10, 2025Clinical ophthalmologyOpen Access

Anatomical and Functional Outcomes of Anti-VEGF Therapy in Pachychoroid Neovasculopathy

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Authors

VSVasilena SitnilskaJPJ PohlYTYi Tang

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Overview

Retrospective analysis shows improvement in BCVA and anatomical measures in patients with pachychoroid neovasculopathy, suggesting ongoing treatment may be necessary.

Key Points

  • Anti-VEGF therapy showed significant improvement in best-corrected visual acuity and anatomical measures over time, and
  • Among 40 patients, 85% achieved a 'completely dry' status on OCT following treatment, indicating positive anatomical change, but
  • The study used a retrospective analysis of cases with treated pachychoroid neovasculopathy and included key metrics like BCVA, CRT, and CT, with
  • Despite improvements, the recurrence rate of 82.4% within months highlights the challenges in sustaining treatment effects.

Cite This Study

Sitnilska et al. (2025) studied this question.

synapsesocial.com/papers/68c1c23d54b1d3bfb60efd1fhttps://doi.org/10.2147/opth.s529840
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Two-year treatment outcome of photodynamic therapy combined with anti-vascular endothelial growth factor therapy for pachychoroid neovasculopathy2025
  2. 2Long-term outcomes of anti-vascular endothelial growth factor therapy with and without posterior scleral reinforcement on myopic maculopathy in myopic choroidal neovascularization eyes2024
  3. 3Two-year Outcome of Intravitreal Anti-vascular Endothelial Growth Factor Therapy for Polypoidal Choroidal Vasculopathy2024
  4. 4Choroidal Neovascular Membrane in Pediatric Patients: Long-Term Outcomes of Anti-VEGF Therapy.2025
  5. 5Intravitreal Anti-Vascular Endothelial Growth Factor Treatment for Choroidal Neovascularization in Choroidal Osteoma: A Pilot Study2026