What type of study is this?

This is a In Vitro Study study (also classified as: Animal Study).

September 10, 2025Bioinformation

Exploration of bacteriophage therapy as a viable alternative to combat antibiotic-resistant bacterial infections: A comprehensive in vitro and in vivo evaluation

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Authors

TMT K Mehta SVSaket Verma AKAmberpreet Kaur Khangura

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Overview

Systematic evaluation demonstrates efficacy of bacteriophage therapy against antibiotic-resistant bacteria, highlighting its potential as a safe alternative.

Key Points

Bacteriophage therapy led to a significant reduction in bacteria levels, improving treatment outcomes against resistant strains.
Phage treatment reduced bacterial counts up to 4.5 log₁₀ CFU/mL while improving survival rates in mice to 85% in in vivo models.
This study employed both in vitro and in vivo approaches to comprehensively assess phage efficacy against multidrug-resistant infections.
Findings suggest that bacteriophage therapy may safely manage antibiotic-resistant infections, preserving beneficial gut microbiota.

Cite This Study

Mehta et al. (2025) studied this question.

synapsesocial.com/papers/68c1c23d54b1d3bfb60efdb1 https://doi.org/10.6026/973206300212176

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September 10, 2025Bioinformation

Exploration of bacteriophage therapy as a viable alternative to combat antibiotic-resistant bacterial infections: A comprehensive in vitro and in vivo evaluation

View Full Paper

Ask AI

Bookmark

Authors

TMT K Mehta SVSaket Verma AKAmberpreet Kaur Khangura

Discussion

Member takes

Overview

Systematic evaluation demonstrates efficacy of bacteriophage therapy against antibiotic-resistant bacteria, highlighting its potential as a safe alternative.

Key Points

Bacteriophage therapy led to a significant reduction in bacteria levels, improving treatment outcomes against resistant strains.
Phage treatment reduced bacterial counts up to 4.5 log₁₀ CFU/mL while improving survival rates in mice to 85% in in vivo models.
This study employed both in vitro and in vivo approaches to comprehensively assess phage efficacy against multidrug-resistant infections.
Findings suggest that bacteriophage therapy may safely manage antibiotic-resistant infections, preserving beneficial gut microbiota.

Cite This Study

Mehta et al. (2025) studied this question.

synapsesocial.com/papers/68c1c23d54b1d3bfb60efdb1 https://doi.org/10.6026/973206300212176

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