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September 10, 2025Medical Research Archives

Comparative Study of Using Norepinephrine Infusion versus Dopamine in Hemodynamically Unstable Patients at Surgical Intensive Care Unit

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Authors

MNMuhammad NaeemMKMuhammad Ibrahim KhaskheliRTRafia Tabassusm

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Overview

Retrospective cohort study compares outcomes of norepinephrine and dopamine in hemodynamic instability, suggesting norepinephrine may be safer.

Key Points

  • Norepinephrine administration led to lower mortality rates compared to dopamine in critically ill patients.
  • Patients receiving norepinephrine had better rates of self-ventilation and mechanical ventilation outcomes.
  • Dopamine use was associated with higher antibiotic usage among patients in the surgical intensive care unit.
  • Results support norepinephrine as a first-line vasopressor in managing hemodynamic instability.

Cite This Study

Naeem et al. (2025) studied this question.

synapsesocial.com/papers/68c1c32754b1d3bfb60f1076https://doi.org/10.18103/mra.v13i7.6720
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Postoperative norepinephrine versus dopamine in patients undergoing noncardiac surgery: a propensity-matched analysis using a nationwide intensive care database2023 · 2 citations
  2. 2Norepinephrine Versus Dopamine as Vasoactive Therapy in Cardiogenic Shock: Association With 28-Day Mortality in a Retrospective Cohort Study2026
  3. 3Norepinephrine Versus Dopamine as Initial Vasoactive Therapy in Neonatal Septic Shock: A Randomized Controlled Trial in a Tertiary Care Neonatal Intensive Care Unit in Eastern India2026
  4. 4Dopamine versus norepinephrine in the treatment of cardiogenic shock2017 · 50 citations
  5. 5Exploration of different statistical approaches in the comparison of dopamine and norepinephrine in the treatment of shock: SOAP II2024 · 7 citations