Observational study identifies chronic liver disease causes and complications in adults, highlighting the role of alcohol and hepatitis B.
.1. Background Chronic liver disease in the clinical context is a disease process that causes progressive destruction and regeneration of the liver parenchyma leading to fibrosis and cirrhosis. Over the years, liver disease rates are steadily increasing. So, we conducted the study with the objective of identifying the factors leading to hospitalization in patients of chronic liver disease in a tertiary care hospital in New Delhi, India. 1.2. Materials and Methods An observational cross-sectional study was conducted at the Department of Medicine, Post Graduate Institute of Medical Sciences and Research (PGIMER), Dr RML Hospital, New Delhi, India from November 2018 to March 2020. All patients with chronic liver disease admitted in the hospital during the study period were included in the study. Inclusion criteria were patients with Chronic Liver Disease (CLD) of any cause in both sexes in the age group 18-75 years. The data was collected from 100 participants. 1.3. Results The mean (SD) age of the study population was 48.29 (9) years. Most of them (80%) were males. Weakness and yellowish discoloration were the most common symptoms reported in 92 and 91 study participants respectively. Alcohol usage was the most common cause (64%) followed by hepatitis B infection (16%). Hepatic encephalopathy was the most common complication observed in 36 study participants followed by upper gastrointestinal bleeding in 30 participants. 1.4. Conclusion The most common factor for hospitalization of chronic liver disease patients was found to be alcohol related and hepatic encephalopathy was the most common complication. So, public awareness regarding alcohol de-addiction, hepatitis B immunization, and adequate treatment of chronic liver disease can cause less hospitalization and mortality.
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Mishra et al. (2025) studied this question.
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