Observational evidence indicates systemic thrombolysis can halve mortality risk in pulmonary embolism, highlighting the role of interdisciplinary collaboration.
Traditionally, catheter-based recanalization techniques have been the gold standard for treating myocardial infarction and stroke. However, interventional treatments for pulmonary embolism (PE) have often been relegated to second-line measures. While systemic thrombolysis has been shown to potentially halve the mortality risk in patients with high-risk PE, its application remains limited outside specialized medical facilities. Recent advancements in thrombectomy devices have signicantly altered clinical practice, addressing a critical therapy gap for both intermediate and high-risk pulmonary emboli. To ensure these new therapies demonstrate safety and efcacy, current treatment paradigms must evolve; promising observational evidence is emerging, and randomized controlled trials are underway. Given their expertise in invasive procedures and diagnostic imaging, interventional radiologists are ideally positioned to play a pivotal role in interdisciplinary pulmonary embolism response teams, which are essential for delivering tailored therapies.
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Sodhi et al. (2025) studied this question.
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