Study the Association of Serum Lipid Profile with Hypertension in Kingdom of Saudi Arabia- A Case Control Study

Introduction: The highest rates of morbidity and mortality in Saudi Arabia are caused by heart disease, which is significantly increased by hypertension and dyslipidemia. The aim of this research was to compare the lipid profiles of hypertension patients in Saudi Arabia to those of normotensive control people to see if there was any relation. Methods: This Case Control study was performed at “Wahat Alshifa polyclinic Madinah Munawarah” Saudi Arabia, with 235 participants 201 hypertension patients and 34 normotensive controls. Socio-demographic information, measurements of anthropometric factors, blood pressure levels, and lipid profile information, including total cholesterol, triglycerides, low density lipoproteins (LDL), and high-density lipoproteins (HDL), were all gathered. Results: In this study lipid profile association between hypertensive and controls was as followed, high Total cholesterol (TC) (65.2% vs. 35.3%; P: 0.001), high triglyceride (TG) (77.6% vs. 61.8%; P: 0.047), low HDL (95.5% vs. 70.6%; P: 0.0001) and high LDL (72.6% vs. 50%; P: 0.008). While in our study hypertensive patients had 3.43and 2.14 times higher TC and TG, 2.65 times higher LDL, and 8.88 times lower HDL than normotensives. Conclusion: In conclusion, this study finding showed the highly significant association between hypertension and lipid disorders. In order to prevent heart attacks, strokes, as well as other multiple medical conditions, hypertensive individuals in Saudi Arabia need to get their blood pressure & lipid profile measured on a regular basis.