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September 10, 2025Indus journal of bioscience research.Open Access

Comparison of Efficacy of Combination Therapy (Tamsulosin + Solifenacin) Versus Monotherapy (Tamsulosin) Alone for Double J Stent Related Lower Urinary Tract Symptoms

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Authors

WJWaleed JavaidMAMuhammad AkmalZSZaighum Sohail

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Overview

Randomized trial shows combination therapy improves lower urinary tract symptoms in DJ stent patients, indicating better management strategies.

Key Points

  • Patients receiving combination therapy experienced a significantly greater reduction in IPSS scores compared to those on monotherapy.
  • The combination group's mean IPSS scores decreased from 9.55 to 4.79, while the monotherapy group reduced scores from 10.95 to 6.33.
  • Randomized sampling divided sixty patients aged 18 to 40 into two groups, evaluating symptoms with the IPSS questionnaire at baseline and after four weeks.
  • These findings suggest that dual pharmacotherapy may enhance symptom relief and patient comfort during stent indwelling.

Cite This Study

Javaid et al. (2025) studied this question.

synapsesocial.com/papers/68c1c9dd54b1d3bfb60f2e85https://doi.org/10.70749/ijbr.v3i7.1770
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Comparative Efficacy of Tamsulosin and Solifenacin in Managing Double J Stent-Related Symptoms: A Randomized Clinical Study Using the USSQ Tool2025
  2. 2Comparison of tamsulosin with placebo in relieving ureteral stent related lower urinary tract symptoms.2025
  3. 3Comparative Approaches in Treating Double-J Stent Syndrome: Monotherapy or Combination Therapy?2024 · 5 citations
  4. 4A comparative study of morbidity and symptom severity among double-J stented patients with and without tamsulosin administration2024
  5. 5Double versus standard dose of tamsulosin with solifenacin for management of ureteral stent related symptoms2025