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September 10, 2025MicrobiomeOpen Access

The genetic diversity and populational specificity of the human gut virome at single-nucleotide resolution

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Analysis reveals genetic stratification in gut virome between Chinese and non-Chinese populations, suggesting implications for health.

Genetic stratification in the gut virome may influence bacterial infection susceptibility, with 18.9% variance identified.
The study analyzes 120,568 viral genomes from 3234 fecal samples across China, contributing to global gut viral diversity understanding.
Single-nucleotide variations correlate with human traits like age and gastrointestinal issues, enhancing insights into health.
Distinct genetic components link population-specific viruses with multidrug resistance, indicating important health implications.

Wang et al. (2025) studied this question.

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