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This is a Quantitative Study study.

November 4, 2025Open Access

A genomic atlas of the human gut virome elucidates genetic factors shaping host interactions

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Analysis of metagenomic sequencing data suggests genomic features like DNA methyltransferases enhance phage diversity in gut microbiome.

Host range breadth strongly associates with phage prevalence across diverse gut microbiomes.
In-depth functional annotations and protein structures were developed in the Unified Human Gastrointestinal Virome.
Comparative analysis included 873,994 viral genomes from geographically diverse populations, enhancing virome understanding.
Findings underscore how specific genomic features impact global phage distribution in the gut.

Camargo et al. (2025) studied this question.

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