The acylation reaction demonstrates regioselectivity in carbazole derivatives, suggesting broad functional group compatibility.
Carbazole scaffolds exhibit diverse applications in materials and biomedical research. We report here a regioselective acylation reaction of carbazole derivatives via a six-membered palladacycle intermediate, featuring the broad functional group compatibility and unique regioselectivity. Additionally, the tolerance of bromo substituents enables further derivatization of the products.
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Herington et al. (2025) studied this question.
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