What type of study is this?

This is a Systematic Review study (also classified as: Meta-Analysis).

Efficacy of daily versus alternate day oral iron supplementation for management of anaemia among general population: a systematic review and meta-analysis

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Systematic review compares oral iron supplementation strategies for iron deficiency anemia in general population, indicating similar efficacy.

Both daily and alternate-day oral iron supplementation are comparably effective for treating iron deficiency anemia.
Pooled analysis shows a small increase in hemoglobin with daily dosing, but it is statistically non-significant (MD: 0.28, p = 0.06).
Risk of bias across included studies was low to moderate, with certainty of evidence rated very low due to heterogeneity.
Adverse effects were similar, though metallic taste was more frequent with daily dosing, suggesting better tolerability for alternate-day.

Dhanvijay et al. (2025) studied this question.

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View Full Paper

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Authors

Systematic review compares oral iron supplementation strategies for iron deficiency anemia in general population, indicating similar efficacy.

Both daily and alternate-day oral iron supplementation are comparably effective for treating iron deficiency anemia.
Pooled analysis shows a small increase in hemoglobin with daily dosing, but it is statistically non-significant (MD: 0.28, p = 0.06).
Risk of bias across included studies was low to moderate, with certainty of evidence rated very low due to heterogeneity.
Adverse effects were similar, though metallic taste was more frequent with daily dosing, suggesting better tolerability for alternate-day.

Dhanvijay et al. (2025) studied this question.

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