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September 10, 2025Open Access

From Detection to Delay: Real-World Gaps in Post-Cologuard® Colonoscopy Adherence

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Authors

MKMuhammad Ali Ibrahim KaziIQImran QureshiASAkshay Sharma

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Overview

Retrospective cohort study investigates colonoscopy adherence after positive Cologuard tests, highlighting significant gaps.

Key Points

  • Only 44% of patients with positive Cologuard results underwent follow-up colonoscopy within 12 months.
  • Among those who underwent the procedure, 5.8% were diagnosed with malignant neoplasms and 32.7% with benign neoplasms.
  • The study utilized a retrospective cohort study approach using the TriNetX database to analyze patient data.
  • Findings indicate a high false positive rate, with 67.3% of patients not having significant findings post-Cologuard test.

Cite This Study

Kazi et al. (2025) studied this question.

synapsesocial.com/papers/68c1d5e554b1d3bfb60f8825https://doi.org/10.21203/rs.3.rs-7367945/v1
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1From Detection to Delay: Real-World Gaps in Post-Cologuard® Colonoscopy Adherence2025
  2. 2Improving colorectal cancer screening through Cologuard education: a quality improvement initiative in an urban primary care clinic2025
  3. 3The Utility of Cologuard ® for CRC Screening After a Normal Colonoscopy2024
  4. 4Rates and Timing of Follow-up Colonoscopy After a Positive Stool-Based Test in an Integrated Health System2026
  5. 5Invasive Colorectal Cancer Detected up to 3 Years after a Colonoscopy Negative for Cancer2003 · 70 citations