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September 10, 2025Bulletin of the Korean Chemical SocietyOpen Access

A lipid droplet‐selective fluorescent probe for real‐time imaging and polarity sensing

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Authors

YLY. LeeBHBokyeong HwangBSBingqing Sun

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Overview

Fluorescence imaging detects changes in lipid droplets in living cells, suggesting early indicators of metabolic disorders.

Key Points

  • Real-time visualization of lipid droplets allows for early detection of hepatic steatosis in living cells.
  • The probe demonstrated high lipid selectivity and pronounced polarity sensitivity for accurate monitoring.
  • Analysis used advanced methods like density functional theory and confocal laser scanning microscopy.
  • This technology could enhance understanding of metabolic disorders linked to lipid droplets.

Cite This Study

Lee et al. (2025) studied this question.

synapsesocial.com/papers/68c1d5e554b1d3bfb60f8a2ahttps://doi.org/10.1002/bkcs.70061
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Dynamic Imaging of Lipid Droplets in Cells and Tissues by Using Dioxaborine Barbiturate-Based Fluorogenic Probes2024 · 7 citations
  2. 2Super-Resolution Microscopic Imaging of Lipid Droplets in Living Cells via Carbonized Polymer Dot-Based Polarity-Responsive Nanoprobe2024 · 2 citations
  3. 3Lipid droplet-targeted near-infrared fluorescent probes for polarity detection and identification of non-alcoholic fatty liver disease2025 · 3 citations
  4. 4Tetramic Acid‐Derived Blue‐Emitting Fluorescent Probe for Selective Lipid Droplet Imaging in Live Cells and Zebrafish2026
  5. 5A fluorogenic and ultrabright probe for imaging of lipid droplets in live and fixed cells2026