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September 28, 2025New Journal of Chemistry

Lipid droplet-targeted near-infrared fluorescent probes for polarity detection and identification of non-alcoholic fatty liver disease

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Authors

JLJiale LiWannan Medical CollegeQZQitao ZhaoMinistry of Education of the People's Republic of ChinaJWJie WangWannan Medical College

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Implication

NIR probe LS3 identifies polarity differences in tissue, suggesting potential for NAFLD diagnosis.

Key Points

  • The NIR probe LS3 enables differentiation of NAFLD from healthy tissue, offering new diagnostic potential.
  • High polarity sensitivity of the probe allows wash-free imaging of lipid droplets in live tissues.
  • This approach could improve diagnostic techniques for liver diseases, enhancing patient outcomes.
  • Adoption of advanced imaging technologies could lead to better monitoring of liver health.

Cite This Study

Li et al. (2025) studied this question.

synapsesocial.com/papers/68d9052141e1c178a14f5058https://doi.org/10.1039/d5nj03211c
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Also Consider

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  1. 1Membrane microdomains: Structural and signaling platforms for establishing membrane polarity2023 · 15 citations
  2. 2Testing the polar auxin transport model with a selective plasma membrane H+‐ATPase inhibitor2022 · 17 citations
  3. 3A fluorescent probe for lipid droplet polarity imaging with low viscosity crosstalk2023 · 31 citations