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This is a Literature Review study.

Twiddler's Syndrome: a Rare Complication of Pacemakers

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Case studies highlight stimulation failure in patients with pacemakers, suggesting risks associated with twiddler's syndrome.

Twiddler's syndrome causes severe stimulation failure in patients with pacemakers, necessitating immediate intervention.
Key risk factors include obesity, psychiatric disorders, and poorly fixed pulse generators, which may lead to complications.
This analysis emphasizes recent case studies published in medical journals regarding pacemaker-related complications.
Understanding twiddler's syndrome is crucial for enhancing pacemaker efficacy and addressing patient concerns.

Santos et al. (2025) studied this question.

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