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September 10, 2025EP EuropaceOpen Access

Implementation of lead V8 as a simple non-invasive tool to improve patient selection in CRT and guide LV lead placement

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Authors

JJJacqueline JozaElectrophysiologyJKJohan van KollElectrophysiologyVRVadivelu RamalingamSri Ramachandra Institute of Higher Education and Research

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Implication

Observational analysis shows V8 improves LV lead positioning and correlates with QLV interval, suggesting better patient outcomes.

Key Points

  • NDAT in lead V8 strongly correlates with the QLV interval, indicating it as a useful marker for locating LV leads.
  • The study included 43 patients, demonstrating a mean difference of only 1 ms in NHAT comparison with a strong correlation of r = 0.895.
  • Using lead V8 for measuring activation times allows for accurate localization of LV leads without needing additional tools.
  • These findings support lead V8's potential to refine patient selection and optimize the delivery of CRT.

Cite This Study

Joza et al. (2025) studied this question.

synapsesocial.com/papers/68c1d7fe54b1d3bfb60fa5aahttps://doi.org/10.1093/europace/euaf194
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Lead V8 as a simple non-invasive tool for assessing lv activation delay across different conduction abnormalities2026
  2. 2The resynchronization effect in left bundle branch pacing can be evaluated non-invasively with implementation of lead V82026
  3. 3Non-invasive assessment of left atrial activation using lead V8 during Bachmann bundle pacing2026
  4. 4Local electrogram delay recorded from left ventricular lead at implant predicts response to cardiac resynchronization therapy: Retrospective study with 1 year follow up2012 · 25 citations
  5. 5Non-invasive estimation of QLV from the standard 12-lead ECG in patients with left bundle branch block2022 · 7 citations