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September 10, 2025Open Access

Effectiveness of attexis, a Digital Intervention Based on Cognitive Behavioral Therapy for Adults with ADHD: A Randomized Controlled Trial

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Authors

RDRoberto D’AmelioLBLinda T. BetzSJSarah M. Jow

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Overview

Randomized controlled trial evaluated a digital intervention for reducing ADHD symptoms in adults, suggesting it complements existing care.

Key Points

  • The intervention group experienced significantly lower ADHD symptom severity after 3 months, indicating its effectiveness.
  • Mean difference in ADHD symptoms was –5.0 points at T1, with a large effect size (d = 0.85, p < .001), confirming substantial improvements.
  • This pragmatic randomized controlled trial assessed the digital intervention against treatment as usual for 337 adults with ADHD.
  • The findings highlight that attexis is a safe adjunct to routine care, potentially expanding access to psychosocial treatment for adults with ADHD.

Cite This Study

D’Amelio et al. (2025) studied this question.

synapsesocial.com/papers/68c1d98554b1d3bfb60fb4fbhttps://doi.org/10.1101/2025.08.27.25334574
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Effectiveness of <i>attexis</i> , a digital intervention based on cognitive behavioral therapy for adults with ADHD: a randomized controlled trial2026 · 2 citations
  2. 2A 5-week Digital Intervention to Reduce Attention Problems in Children With ADHD: A Double-Blind Randomized Controlled Trial2024 · 1 citations
  3. 3Efficacy of an Unguided Digital Intervention for Adults With Attention-Deficit/Hyperactivity Disorder: A Randomized Controlled Trial.2026
  4. 4Cognitive-behavioral and mindfulness-based cognitive therapies for adults with attention-deficit/hyperactivity disorder and cognitive disengagement syndrome: a randomized controlled trial2026
  5. 5Bridging the Gap: Digital CBT for Adults Managing ADHD Challenges2025