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September 10, 2025Ibn AL- Haitham Journal For Pure and Applied ScienceOpen Access

Synthesis and Antioxidant Characteristics of Novel Heterocyclic Derivatives from 2-Thiol-5-Phenyl-1,3,4-Oxadiazole Compounds

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Authors

SJSajid JamalMAM. Rafiuddin Ahmed

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Overview

This research demonstrates antioxidant properties of 1,3,4-oxadiazole derivatives in radical inhibition, suggesting therapeutic potential.

Key Points

  • The synthesized compounds showed significant antioxidant activity, especially against DPPH radicals.
  • Compounds 10 and 13 exhibited stronger inhibition of DPPH radicals compared to BHT, a common antioxidant.
  • The synthesis process involved multiple steps, including reactions with hydrazine hydrate and ethyl chloroacetate.
  • The findings support further research into the therapeutic capabilities of these novel compounds against oxidative stress.

Cite This Study

Jamal et al. (2024) studied this question.

synapsesocial.com/papers/68c1e07554b1d3bfb60fcdf9https://doi.org/10.30526/37.4.3340
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