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September 10, 2025Kerbala journal of pharmaceutical sciences.

Studying the Role of L-Thyroxine in Long-Term Management of Hypothyroidism: A Comparative Analysis with Healthy Control

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Authors

NMNabaa Zuhair MiranSJShaima JabbarZAZahraa Abed Al-kareem

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Overview

Cross-sectional study evaluated L-thyroxine effects on metabolic markers in hypothyroid women, suggesting important management insights.

Key Points

  • Weight, blood pressure, and BMI differed significantly between hypothyroid patients and healthy controls, indicating health disparities.
  • Patients showed decreased FT4 and increased TSH levels, revealing complications in thyroid regulation and metabolic health.
  • Lower HOMA-IR indices and glucose metabolism issues highlighted the relationship between thyroid dysfunction and metabolic parameters.
  • Long-term L-thyroxine therapy influenced TSH levels, suggesting its role in managing hypothyroidism and metabolic health.

Cite This Study

Miran et al. (2024) studied this question.

synapsesocial.com/papers/68c1e07d54b1d3bfb60fd2b0https://doi.org/10.62472/kjps.v15.i24.35-56
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Evaluation of the lipid profile level in patients with hypothyroidism2024
  2. 2LEVOTHYROXINE AND LIOTHYRONINE IN HYPOTHYROIDISM: A COMPARATIVE REVIEW OF SAFETY AND EFFICACY2026
  3. 3Triiodothyronine/Thyroxine Ratio as a Marker of Clinical Response to Levothyroxine Replacement in Patients With Hypothyroidism2024 · 1 citations
  4. 4Biochemical and Hematological Assessment in Patients With Thyroid Dysfunction2024
  5. 5Body weight and waist circumference are differentially associated with the response to L-thyroxine treatment in primary hypothyroidism2026