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September 10, 2025Biolohichni systemy

Quantitative Analysis of Reg1α and Tgfb1 Gene Expression in Gastric Mucosa Cells of Rats Under the Effects of Immobilized-Water Immersion Stress

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Authors

AHA. S. HuetKDK. DvorshchenkoDGD. M. Grebinyk

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Overview

Analysis reveals increased reg1a and tgfb1 gene expression in gastric mucosa under immobilization stress, suggesting potential roles in recovery.

Key Points

  • Increased expression of reg1a and tgfb1 genes was observed at various time points during stress exposure, indicating their role in gastric mucosa response.
  • Gene expression was measured using RT-qPCR, showing significant variation at 0.5, 1, 2, and 3 hours under stress conditions.
  • There was a noted return to control levels of gene expression at 12 to 24 hours after stress withdrawal, highlighting the recovery process.
  • A positive correlation between reg1a and tgfb1 indicates their synergistic effect in the regeneration of gastric mucosa post-ulcer formation.

Cite This Study

Huet et al. (2024) studied this question.

synapsesocial.com/papers/68c1e17054b1d3bfb60fe8b8https://doi.org/10.31861/biosystems2024.02.227
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