The specific features of epidemic complications in cholera at the present-day stage

There is presently a real threat of cholera importation by all modes of transport from the countries endemic for this infection. 70% of importations have been noted in type III, subtype A, areas (the Central and Volga Federal Districts) where there are the largest number of state border passage points in the Russian Federation by all modes of transport. For the epidemiological estimation of the population's migration, based on the analysis of international passenger traffic, the migration turnover coefficient was introduced and tested in the Rostov Region. This index is important in assessing the adjustment of the types of areas by the epidemic manifestations of cholera to reduce the economic cost associated with this disease. The tactics for examination of migrants with acute enteric infections from cholera-endemic countries for cholera, continuous monitoring of environmental objects, and great attention to the training of bacteriologists and the quality of laboratory tests are warranted. Vibrio cholerae comprises more than 200 serological O variants. Among them, there are virulent vibrions that are able to induce diseases and that are epidemically dangerous; vibrions that habitat in the water reservoirs, those are safe for humans or pathogenic, those that can cause some cases of diarrhea. The non-O1/non-O139 strains having the ctx gene are encountered with a certain frequency. It is necessary to interrogate such strains isolated from humans and environmental objects.