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The Frequency and Diagnostic Value of HHV-6 Detection in CSF of Immunocompetent Children

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Detection of HHV-6 DNA in CSF was found in only 2.9% of cases, mostly indicating no meningoencephalitis.
Only two cases of confirmed HHV-6 meningoencephalitis occurred out of 712 patients, a rare finding.
Assessment utilized qualitative PCR on CSF samples from suspected meningoencephalitis cases over a 12-year period.
These results suggest that HHV-6 detection in CSF requires careful interpretation in clinical diagnoses.

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Retrospective analysis assessed the frequency and diagnostic value of HHV-6 in CSF, highlighting its implications for meningoencephalitis diagnosis.

Nikolskiy et al. (2025) studied this question.

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Retrospective analysis assessed the frequency and diagnostic value of HHV-6 in CSF, highlighting its implications for meningoencephalitis diagnosis.