Why the study?
What is the prevalence of human parechovirus and human herpes virus-6 in the cerebrospinal fluid of infants tested for enterovirus or herpes simplex virus?
What is the prevalence of human parechovirus and human herpes virus-6 in the cerebrospinal fluid of infants tested for enterovirus or herpes simplex virus?
Five percent of infants under 6 months tested for EV or HSV have HPeV or HHV-6 in their CSF, suggesting targeted testing may increase diagnostic yield.
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May support targeted testing to increase diagnostic yield in young infants; hypothesis-generating pending prospective validation.
Messacar et al. (2015) studied this question.