Analysis identifies long-term nonprogressors and elite controllers in HIV-infected individuals, indicating immunological factors impact disease progression.
By analyzing a large cohort of HIV-infected persons in the Moscow Region, the authors studied the patients with a disease duration of more than 3000 days. Long-term nonprogressors and elite-controllers of HIV infection were identified and characterized. The increase in the total count of T lymphocytes (CD3+) and cytotoxic T lymphocytes (CD8+) may be considered to be factors that deter the progression of the disease.
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Kaminsky et al. (2010) studied this question.
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