Computer simulation predicts temperature impact on melanoma in human skin, indicating potential treatment insights.
The paper presents the results of computer simulation of the temperature effect on the tumor of the human skin in a dynamic mode. The physical, mathematical and computer models of the human skin with oncological neoplasm (melanoma) were built with regard to thermophysical processes, blood circulation, heat exchange, metabolic processes and phase transition. As an example, the case is considered when a work tool is located on the tumor surface, the temperature of which changes cyclically according to a predetermined law in the temperature range [-50 ÷ +50] °C. Temperature distributions in the tumor and various layers of human skin in the cooling and heating modes have been determined. The results obtained make it possible to predict the depth of freezing and heating of biological tissue, in particular a tumor, at a given temperature effect. Bibl. 59, Fig. 6, Tabl. 2.
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Anatychuk et al. (2020) studied this question.
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